If you mean this manager it’s a tool to create the initial vfio configuration for the passthrough. You can do it by hand.

At the end of the day though after all of our storage tests conducted on Clear Linux, EXT4 came out to being just 2% faster than F2FS for this particular Intel Xeon Gold 5218 server paired with a Micron 9300 4TB NVMe solid-state drive source

I’ll suggest XFS.